Publications
Selected publications
Key recent and landmark papers that underpin our programmes (selected).
Nature Communications
The genetic evolution of acral melanoma
PNAS Nexus
Distinct senescence mechanisms restrain progression of dysplastic nevi
Genome Medicine
Integrated genomic analyses of acral and mucosal melanomas nominate novel driver genes
Journal of Experimental Medicine
Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors
Leukemia
Synthetic lethal targeting of TET2‑mutant HSPCs with TOP1‑targeted drugs and PARP1 inhibitors
Genome Research
Ribosomal DNA harbours an evolutionarily conserved clock of biological aging
PLOS Genetics
Ribosomal DNA copy number amplification and loss in human cancers is linked to tumour genetic context, nucleolus activity, and proliferation
Nucleic Acids Research